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Medscape – Obesity management dosing for Alli, Xenical (orlistat), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes It was approved by the FDA for use in combination with a reduced-calorie diet in 1999 15 This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter 16 and prescription go drugbank com articles A1728gpnotebook com pages obesity orlistatreference medscape com drug alli-xenical-orlistat-342068— medicine com drug orlistat hcpDescription Orlistat is used with a reduced-calorie diet and regular exercise to help with weight loss This medicine is used in people with overweight or obesity This medicine is available both over-the-counter (OTC) and with your doctor’s prescription Orlistat reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI) — rxlist com orlistat generic-drug htmOrlistat is a gastric and pancreatic lipase inhibitor indicated for the management of obesity It is the first antiobesity agent that is not a centrally acting appetite suppressant; instead, it decreases absorption of dietary fat in the gastrointestinal tract Orlistat is used together with a reduced-calorie diet and weight maintenance to treat obesity Learn about side effects, interactions and indications — drugs com orlistat htmlWhat Is Orlistat and How Does It Work? Orlistat is a gastrointestinal lipase inhibitor that works by blocking the absorption of 25% of the fat in a meal and is used for weight loss in overweight adults, 18 years and older when used along with a reduced-calorie and low-fat diet Orlistat is a lipase inhibitor used with a mildly hypocaloric diet to aid weight loss in adults with BMI 28+ with risk factors or BMI 30+; continue beyond 3 months only if 5% weight loss, and avoid co-prescribing with other weight‑loss drugs Includes Orlistat indications, dosage administration, pharmacology, mechanism onset duration of action, half-life, dosage forms, interactions, warnings, adverse Feb 24, 2025 · Orlistat is used together with a reduced-calorie diet and weight maintenance to treat obesity Learn about side effects, interactions and indications Orlistat is a gastrointestinal lipase inhibitor that works by blocking the absorption of 25% of the fat in a meal and is used for weight loss in overweight adults, 18 years and older when used along with a reduced-calorie and low-fat diet Learn about side effects, drug interactions, dosages, and more go drugbank com drugs DB01083Jun 13, 2005 · Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes — mayoclinic org drugs-supplements orlistat-oral-route drg-20065184Oct 1, 2025 · When using orlistat, your diet should contain no more than 30% of calories as fat More fat in your diet will increase the side effects of this medicine Your diet should be nutritionally balanced, and your daily intake of fat, carbohydrates, and protein should be distributed over three main meals Orlistat (tetrahydrolipstatin) is an anti-obesity medication approved by the US Food and Drug Administration (FDA) This medication is a saturated derivative derived from the endogenous lipstatin found in Streptomyces toxytricini Orlistat is used to manage obesity by reversibly inhibiting ga …— drugs com monograph orlistat htmlOrlistat is a gastric and pancreatic lipase inhibitor indicated for the management of obesity It is the first antiobesity agent that is not a centrally acting appetite suppressant; instead, it decreases absorption of dietary fat in the gastrointestinal tract pubmed ncbi nlm nih gov 31194359Feb 14, 2024 · Orlistat is used to manage obesity by reversibly inhibiting gastric and pancreatic lipases within the gut These lipases play a crucial role in the digestion of dietary fat by breaking down triglycerides into absorbable free fatty acids and monoglycerides Orlistat (Xenical, Alli) is a drug available in prescription and over-the-counter that promotes weight loss Side effects include abdominal pain and discomfort, oily or fatty stools, gas (flatulence), oily spotting on underwear

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